In-line Raman imaging of mixing by herringbone grooves in microfluidic channels.

ABSTRACT: The control over fluid flow achievable in microfluidic devices creates opportunities for applications in many fields. In simple microchannels, flow is purely laminar when one solvent is used, and hence, achieving reliable mixing is an important design consideration. Integration of structures, such as grooves, into the channels to act as static mixers is a commonly used approach. The mixing induced by these structures can be validated by determining concentration profiles in microfluidic channels following convergence of solvent streams from separate inlets. Spatially resolved characterisation is therefore necessary and requires in-line analysis methods. Here we report a line-focused illumination approach to provide operando, spatially resolved Raman spectra across the width of chann

SUBMITTER: Klement WJN 

PROVIDER: S-EPMC11235414 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature