Dopamine agonist serum concentrations and impulse control disorders in Parkinson's disease.

ABSTRACT:

Background and purpose

Impulse control disorders (ICDs) are common among Parkinson's disease patients using dopamine agonists. We wanted to determine whether ICD patients have higher dopamine agonist serum concentrations than those without any sign of ICD.

Methods

Patients who used either pramipexole or ropinirole depot once daily were screened for ICDs using the validated Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale. Those who scored above the cut-off for one or more of the four defined ICDs (gambling, compulsive sexual behavior, compulsive shopping, and binge-eating) were compared in a case-control study to patients who scored zero points (no evidence of ICD) on the same items. They were examined clinically and evaluated using releva

SUBMITTER: Staubo SC 

PROVIDER: S-EPMC11235607 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature