Kinetic features dictate sensorimotor alignment in the superior colliculus.

ABSTRACT: The execution of goal-oriented behaviours requires a spatially coherent alignment between sensory and motor maps. The current model for sensorimotor transformation in the superior colliculus relies on the topographic mapping of static spatial receptive fields onto movement endpoints^1-6. Here, to experimentally assess the validity of this canonical static model of alignment, we dissected the visuo-motor network in the superior colliculus and performed in vivo intracellular and extracellular recordings across layers, in restrained and unrestrained conditions, to assess both the motor and the visual tuning of individual motor and premotor neurons. We found that collicular motor units have poorly defined visual static spatial receptive fields and respond instead to kinetic visual fe

SUBMITTER: Gonzalez-Rueda A 

PROVIDER: S-EPMC11236723 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature