Diet Quality and Epigenetic Aging in the Women's Health Initiative.

ABSTRACT:

Background

Higher diet quality scores are associated with a lower risk for many chronic diseases and all-cause mortality; however, it is unclear if diet quality is associated with aging biology.

Objective

This study aimed to examine the association between diet quality and a measure of biological aging known as epigenetic aging.

Design

A cross-sectional data analysis was used to examine the association between three diet quality scores based on self-reported food frequency questionnaire data and five measures of epigenetic aging based on DNA methylation (DNAm) data from peripheral blood.

Participants/setting

This study included 4,500 postmenopausal women recruited from multiple sites across the United States (1993-98), aged 50 to 79 years, with food frequency q

SUBMITTER: Reynolds LM 

PROVIDER: S-EPMC11236955 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature