Mortality of elderly patients with acute kidney injury undergoing continuous renal replacement therapy: is age a risk factor?

ABSTRACT:

Background

Whether advanced age is associated with poor outcomes of elderly patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) is controversial. This study aimed to evaluate age effect and predictors for mortality in elderly AKI patients undergoing CRRT.

Methods

Data of 480 elderly AKI patients who underwent CRRT were retrospectively analyzed. Subjects were stratified into two groups according to age: younger-old (age, 65-74 years; n = 205) and older-old (age, ≥75 years; n = 275). Predictors for 28-day and 90-day mortality and age effects were analyzed using multivariable Cox regression analysis and propensity score matching.

Results

Urine output at the start of CRRT (adjusted hazard ratio [aHR], 0.99; 95% confidence interval

SUBMITTER: Kim JH 

PROVIDER: S-EPMC11237323 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature