Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City.

ABSTRACT: Highly pathogenic avian influenza viruses of the H5N1 clade 2.3.4.4b were detected in North America in the winter of 2021/2022. These viruses have spread across the Americas, causing morbidity and mortality in both wild and domestic birds as well as some mammalian species, including cattle. Many surveillance programs for wildlife as well as commercial poultry operations have detected these viruses. In this study, we conducted surveillance of avian species in the urban environment in New York City. We detected highly pathogenic H5N1 viruses in six samples from four different bird species and performed whole-genome sequencing. Sequencing analysis showed the presence of multiple different genotypes. Our work highlights that the interface between animals and humans that may give rise to zoonot

SUBMITTER: Meade PS 

PROVIDER: S-EPMC11237497 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature