Surgical Thromboprophylaxis in Patients With Head and Neck Cancer: An Economic Model.

ABSTRACT:

Objective

To quantify postoperative venous thromboembolism (VTE) incidence in head and neck cancer (HNC) patients, and assess the economic implications of chemoprophylaxis.

Study design

Retrospective cost-effective analysis.

Setting

Fifty-three health care organizations.

Methods

The TriNetX Research Network was queried to identify the 1-month VTE rate in HNC patients undergoing neck dissection from 2012 to 2022. A literature search provided additional postsurgical VTE rates in HNC patients. Costs of prophylactic heparin and enoxaparin were obtained from a drug wholesaler, and VTE-associated medical costs were sourced from the literature. A break-even analysis determined the absolute risk reduction (ARR) in the VTE rate necessary for a medication to break-even o

SUBMITTER: Lorenz FJ 

PROVIDER: S-EPMC11237549 | biostudies-literature | 2024 Jul-Sep

REPOSITORIES: biostudies-literature