Quantitative Comparison of the Hydration Capacity of Surface-Bound Dextran and Polyethylene Glycol.

ABSTRACT: We have quantified and compared the hydration capacity (i.e., capability to incorporate water molecules) of the two surface-bound hydrophilic polymer chains, dextran (dex) and poly(ethylene glycol) (PEG), in the form of poly(l-lysine)-graft-dextran (PLL-g-dex) and poly(l-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG), respectively. The copolymers were attached to a negatively charged silica-titania surface through the electrostatic interaction between the PLL backbone and the surface in neutral aqueous media. While the molecular weights of PLL and PEG were fixed, that of dex and the grafting density of PEG or dex on the PLL were varied. The hydration capacity of the polymer chains was quantified through the combined experimental approach of optical waveguide li

SUBMITTER: Perrino C 

PROVIDER: S-EPMC11238585 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature