A multicenter prospective study on the management of hepatoblastoma in children: a report from the Chinese Children's Cancer Group.

ABSTRACT:

Background

This study aimed to identify survival risk factors in Chinese children with hepatoblastoma (HB) and assess the effectiveness of the new treatment protocol proposed by the Chinese Children's Cancer Group (CCCG) in 2016.

Methods

A multicenter, prospective study that included 399 patients with HB from January 2015 to June 2020 was conducted. Patient demographics, treatment protocols, and other related information were collected. Cox regression models and Kaplan-Meier curve methods were used.

Results

The 4-year event-free survival (EFS) and overall survival (OS) were 76.9 and 93.5%, respectively. The 4-year EFS rates for the very-low-risk, low-risk, intermediate-risk, and high-risk groups were 100%, 91.6%, 81.7%, and 51.0%, respectively. The 4-year OS was 100%,

SUBMITTER: Tang MJ 

PROVIDER: S-EPMC11239770 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature