The prognostic value of two histopathologic classification models of ANCA-associated glomerulonephritis: a prospective study.

ABSTRACT:

Background

Berden Classification and anti-neutrophil cytoplasmic antibody (ANCA) Renal Risk Score are classification models for rating renal histology and predicting outcome in patients with ANCA-associated Vasculitis/Glomerulonephritis (AAV/GN). In the present study we compare their ability to predict renal function outcome in short- and long-term follow up.

Methods

Patients with an initial diagnosis of AAV/GN based on kidney biopsy were classified according to Berden and Renal Risk Score, started on the same treatment protocol, and were followed prospectively for up to 60 months. Renal function was recorded at 3mo(T3), 6mo(T6) and 60mo(T60), and results were compared to both classification systems.

Results

Ninety four AAV/GN patients, M/F = 36/58, age = 60.05 (18-82

SUBMITTER: Christodoulou M 

PROVIDER: S-EPMC11239783 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature