The development of a set of key points to aid clinicians and researchers in designing and conducting n-of-1 trials.

ABSTRACT:

Introduction

n-of-1 trials are undertaken to optimise the evaluation of health technologies in individual patients. They involve a single patient receiving treatments, both interventional and control, consecutively over set periods of time, the order of which is decided at random. Although n-of-1 trials are undertaken in medical research it could be argued they have the utility to be undertaken more frequently. We undertook the National Institute for Health Research (NIHR) commissioned DIAMOND (Development of generalisable methodology for n-of-1 trials delivery for very low volume treatments) project to develop key points to assist clinicians and researchers in designing and conducting n-of-1 trials.

Methods

The key points were developed by undertaking a stakeholder workshop

SUBMITTER: Chatters R 

PROVIDER: S-EPMC11241860 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature