Case Studies of a Simulation Workflow to Improve Bone Healing Assessment in Impending Non-Unions.

ABSTRACT: Background: The healing potential of a fracture is determined by mechanical and biological factors. Simulation-based workflows can help assess these factors to assist in predicting non-unions. The aim of this study was the introduction of two use cases for a novel patient-specific simulation workflow based on clinically available information. Methods: The used software is an extension of the "Ulm Bone Healing model" and was applied in two cases with non-union development after fracture fixation to show its principal feasibility. The clinical and radiographic information, starting from initial treatment, were used to feed the simulation process. Results: The simulation predicted non-union development and axial deviation in a mechanically driven non-union. In the case of

SUBMITTER: Maisenbacher TC 

PROVIDER: S-EPMC11242056 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature