Association of Perinatal Cardiovascular Features with Angiotensin System Expressions in Maternal Preeclampsia.

ABSTRACT: We hypothesized and investigated whether prenatal exposure to preeclampsia (PE) would simultaneously affect perinatal cardiovascular features and angiotensin system expressions. This prospective study was composed of mother-neonate dyads with (n = 49) and without maternal preeclampsia (n = 48) in a single tertiary medical center. The neonates exposed to PE had significantly larger relative sizes for the left and right coronary arteries and a higher cord plasma level of aminopeptidase-N, which positively correlated with the maternal diastolic blood pressures and determined the relative sizes of the left and right coronary arteries, whereas the encoding aminopeptidase-N (ANPEP) mRNA level in the PE cord blood leukocytes was significantly decreased, positively correlated with the neona

SUBMITTER: Lin IC 

PROVIDER: S-EPMC11242154 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature