Increased Risk for Infections and Allergic Disease in Hereditary Hemorrhagic Telangiectasia.

ABSTRACT: Background/Objectives: Hereditary hemorrhagic telangiectasia (HHT) is a rare disorder characterized by dilated blood vessels. Different immunological changes have been described in these patients. In this study, the predisposition of patients with HHT to infections and allergic diseases was assessed. Methods: Patients with HHT completed an online survey in English or German. Their data were compared to non-affected partners or friends. Results: A total of 430 out of 588 respondents with HHT answered our questions about infections and allergies. Patients with HHT suffered significantly more often from various types of allergies than their partners, especially type I allergies (n = 226/276, 82%), and had a higher risk for sinusitis, urinary tract infections, pulmonary in

SUBMITTER: Droege F 

PROVIDER: S-EPMC11242906 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature