Blood Lead Mediates the Relationship between Biological Aging and Hypertension: Based on the NHANES Database.

ABSTRACT: Hypertension remains a major global public health crisis due to various contributing factors, such as age and environmental exposures. This study delves into exploring the intricate association between biological aging, blood lead levels, and hypertension, along with examining the mediating role of blood lead levels in the relationship between biological aging and hypertension. We analyzed data from two cycles of the NHANES, encompassing 4473 individuals aged 18 years and older. Our findings indicate that biological aging potentially escalates the risk of hypertension and the incidences of systolic blood pressure (SBP) and diastolic blood pressure (DBP) abnormalities. Utilizing weighted quantile sum (WQS) and quantile g-computation (QGC) model analyses, we observed that exposure to heavy m

SUBMITTER: Wang C 

PROVIDER: S-EPMC11243065 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature