α-Carbonyl Rh-Carbenoid Initiated Cascade Assembly of Diazobarbiturates with Alkylidene Pyrazolones for Synthesis of Spirofuropyrimidines.

ABSTRACT: Catalyzed by Rh₂(esp)₂ (10 mol%) and (±)-BINAP (20 mol%) in DCE at 80 °C, the cascade assembly between diazobarbiturates and alkylidene pyrazolones proceeded readily and produced spiro-furopyrimidines in 38-96% chemical yields. The chemical structure of the prepared spirofuro-pyrimidines was firmly confirmed by X-ray diffraction analysis.

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11243257 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature