Post Natal Microbial and Metabolite Transmission: The Path from Mother to Infant.

ABSTRACT: The entero-mammary pathway is a specialized route that selectively translocates bacteria to the newborn's gut, playing a crucial role in neonatal development. Previous studies report shared bacterial and archaeal taxa between human milk and neonatal intestine. However, the functional implications for neonatal development are not fully understood due to limited evidence. This study aimed to identify and characterize the microbiota and metabolome of human milk, mother, and infant stool samples using high-throughput DNA sequencing and FT-ICR MS methodology at delivery and 4 months post-partum. Twenty-one mothers and twenty-five infants were included in this study. Our results on bacterial composition suggest vertical transmission of bacteria through breastfeeding, with major changes occurring

SUBMITTER: Velez-Ixta JM 

PROVIDER: S-EPMC11243545 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature