Responses to visual motion of neurons in the extrastriate visual cortex of macaque monkeys with experimental amblyopia.

ABSTRACT: Amblyopia is a developmental disorder that results from abnormal visual experience in early life. Amblyopia typically reduces visual performance in one eye. We studied the representation of visual motion information in area MT and nearby extrastriate visual areas in two monkeys made amblyopic by creating an artificial strabismus in early life, and in a single age-matched control monkey. Tested monocularly, cortical responses to moving dot patterns, gratings, and plaids were qualitatively normal in awake, fixating amblyopic monkeys, with primarily subtle differences between the eyes. However, the number of binocularly driven neurons was substantially lower than normal; of the neurons driven predominantly by one eye, the great majority responded only to stimuli presented to the fellow eye. T

SUBMITTER: Van Grootel TJ 

PROVIDER: S-EPMC11244960 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature