The role of oral metformin in preventing and treating age-related macular degeneration: A meta-analysis.

ABSTRACT:

Background

We aimed to perform a meta-analysis to evaluate the effect of metformin on age-related macular degeneration.

Methods

We searched the following databases: PubMed, Scopus, and Web of Science. We included any randomized control trials, prospective and retrospective cohorts, cross-sectional studies, and case-control studies that investigated the effect of metformin on age-related macular degeneration in our meta-analysis with no age or language restrictions. Review manager software, version 5.4 was used to perform the meta-analysis.

Results

Ten studies were included in the meta-analysis with 1,447,470 patients included in the analysis. The pooled analysis showed no statistically significant difference between the metformin group and the non-metformin group rega

SUBMITTER: Elhalag RH 

PROVIDER: S-EPMC11245258 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature