Efficacy of intravenous acetaminophen on postoperative shivering: A meta-analysis of randomized controlled trials.

ABSTRACT:

Purpose

Postoperative shivering (POS) is a common and vital complication after anesthesia, which may result in serious consequences and uncomfortable experiences. Acetaminophen has been used to treat fever and mild to moderate pain. However, there is not enough evidence to prove its advantage for POS. This meta-analysis aimed to explore the prophylactic use of acetaminophen as a valid agent for POS.

Methods

Two researchers independently searched PubMed, the Cochrane Library, and Embase for controlled clinical trials. The meta-analysis of randomized controlled trials (RCTs) was performed by Review Manager.

Results

Nine trials with 856 patients were included in our meta-analysis. Acetaminophen significantly reduced POS compared with placebo (pooled risk ratio [RR]: 0.43

SUBMITTER: Liu J 

PROVIDER: S-EPMC11245272 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature