Inter-joint coordination with and without dopaminergic medication in Parkinson's disease: a case-control study.

ABSTRACT:

Background

How the joints exactly move and interact and how this reflects PD-related gait abnormalities and the response to dopaminergic treatment is poorly understood. A detailed understanding of these kinematics can inform clinical management and treatment decisions. The aim of the study was to investigate the influence of different gait speeds and medication on/off conditions on inter-joint coordination, as well as kinematic differences throughout the whole gait cycle in well characterized pwPD.

Methods

29 controls and 29 PD patients during medication on, 8 of them also during medication off walked a straight walking path in slow, preferred and fast walking speeds. Gait data was collected using optical motion capture system. Kinematics of the hip and knee and coordinated

SUBMITTER: Saegner K 

PROVIDER: S-EPMC11245779 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature