Association between COVID-19 vaccination and menstruation: a state of the science review.

ABSTRACT:

Introduction

Menstrual health is a key patient-reported outcome beyond its importance as a general indicator of health and fertility. However, menstrual function was not measured in the clinical trials of COVID-19 vaccines. The purpose of this review was to synthesise the existing literature on the relationship between COVID-19 vaccination and menstrual health outcomes.

Methods

A PubMed search to 31 October 2023 identified a total of 53 publications: 11 prospective cohort studies, 11 retrospective cohort studies or registry-based cohort studies, and 31 cross-sectional or retrospective case-control studies.

Results

Identified studies were generally at moderate-to-high risk of bias due to retrospective design, interviewer bias, and failure to include a non-vaccinated co

SUBMITTER: Payne LA 

PROVIDER: S-EPMC11246222 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature