Microbiological profile of diabetic foot infections in China and worldwide: a 20-year systematic review.

ABSTRACT:

Introduction

Pathogens causing diabetic foot infections (DFIs) vary by region globally; however, knowledge of the causative organism is essential for effective empirical treatment. We aimed to determine the incidence and antibiotic susceptibility of DFI pathogens worldwide, focusing on Asia and China.

Methods

Through a comprehensive literature search, we identified published studies on organisms isolated from DFI wounds from January 2000 to December 2020.

Results

Based on our inclusion criteria, we analyzed 245 studies that cumulatively reported 38,744 patients and 41,427 isolated microorganisms. DFI pathogens varied according to time and region. Over time, the incidence of Gram-positive and Gram-negative aerobic bacteria have decreased and increased, respectively. Am

SUBMITTER: Qu YD 

PROVIDER: S-EPMC11247326 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature