Tuning the Emission of Bis-ethylenedioxythiophene-thiophenes upon Aggregation.

ABSTRACT: The ability of small lipophilic molecules to penetrate the blood-brain barrier through transmembrane diffusion has enabled researchers to explore new diagnostics and therapies for brain disorders. Until now, therapies targeting the brain have mainly relied on biochemical mechanisms, while electrical treatments such as deep brain stimulation often require invasive procedures. An alternative to implanting deep brain stimulation probes could involve administering small molecule precursors intravenously, capable of crossing the blood-brain barrier, and initiating the formation of conductive polymer networks in the brain through in vivo polymerization. This study examines the aggregation behavior of five water-soluble conducting polymer precursors sharing the same conjugate core but diff

SUBMITTER: Sahalianov I 

PROVIDER: S-EPMC11247477 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature