Considerations for the use of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) in cross-country comparisons of cognitive aging and dementia.

ABSTRACT:

Introduction

Informant reports are a critical component of dementia diagnoses, but the comparability of informant reports across countries is not well understood.

Methods

We compared the performance of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) using population-representative surveys in the United States (N = 3183), England (N = 1050), and India (N = 4047).

Results

Analyses of regression splines and comparisons of model fit showed strong associations between IQCODE and objective cognition at low cognitive functioning in the United States and England; in India, the association was weaker but consistent over the range of cognition. Associations between IQCODE score and informant generation (analysis of variance [ANOVA] p = 0.001), caregiver

SUBMITTER: Nichols E 

PROVIDER: S-EPMC11247671 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature