Prelimbic cortex neural encoding dynamically tracks expected outcome value.

ABSTRACT: Animals must modify their behavior based on updated expected outcomes in a changing environment. Prelimbic cortex (PrL) neural encoding during learning predicts, and is necessary for, appropriately altering behavior based on a new expected outcome value following devaluation. We aimed to determine how PrL neural activity encodes reward predictive cues after the expected outcome value of those cues is decreased following conditioned taste aversion. In one post-devaluation session, rats were tested under extinction to determine their ability to alter their behavior to the expected outcome values (i.e., extinction test). In a second post-devaluation session, rats were tested with the newly devalued outcome delivered so that the rats experienced the updated outcome value within the session (i.

SUBMITTER: Niedringhaus M 

PROVIDER: S-EPMC11247951 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature