Clinically feasible automated MRI volumetry of the brain as a prognostic marker in subjective and mild cognitive impairment.

ABSTRACT:

Background/aims

The number of patients suffering from cognitive decline and dementia increases, and new possible treatments are being developed. Thus, the need for time efficient and cost-effective methods to facilitate an early diagnosis and prediction of future cognitive decline in patients with early cognitive symptoms is becoming increasingly important. The aim of this study was to evaluate whether an MRI based software, NeuroQuant® (NQ), producing volumetry of the hippocampus and whole brain volume (WBV) could predict: (1) conversion from subjective cognitive decline (SCD) at baseline to mild cognitive impairment (MCI) or dementia at follow-up, and from MCI at baseline to dementia at follow-up and (2) progression of cognitive and functional decline defined as an annual increas

SUBMITTER: Amland R 

PROVIDER: S-EPMC11248186 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature