Multiple scattering suppression for in vivo optical coherence tomography measurement using the B-scan-wise multi-focus averaging method.

ABSTRACT: We demonstrate a method that reduces the noise caused by multi-scattering (MS) photons in an in vivo optical coherence tomography image. This method combines a specially designed image acquisition (i.e., optical coherence tomography scan) scheme and subsequent complex signal processing. For the acquisition, multiple cross-sectional images (frames) are sequentially acquired while the depth position of the focus is altered for each frame by an electrically tunable lens. In the signal processing, the frames are numerically defocus-corrected, and complex averaged. Because of the inconsistency in the MS-photon trajectories among the different electrically tunable lens-induced defocus, this averaging reduces the MS signal. Unlike the previously demonstrated volume-wise multi-focus averagi

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC11249682 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature