Imaging modalities for characterising T1 renal tumours: A systematic review and meta-analysis of diagnostic accuracy.

ABSTRACT:

Objectives

International guidelines recommend resection of suspected localised renal cell carcinoma (RCC), with surgical series showing benign pathology in 30%. Non-invasive diagnostic tests to differentiate benign from malignant tumours are an unmet need. Our objective was to determine diagnostic accuracy of imaging modalities for detecting cancer in T1 renal tumours.

Methods

A systematic review was performed for reports of diagnostic accuracy of any imaging test compared to a reference standard of histopathology for T1 renal masses, from inception until January 2023. Twenty-seven publications (including 2277 tumours in 2044 participants) were included in the systematic review, and nine in the meta-analysis.

Results

Forest plots of sensitivity and specificity were pr

SUBMITTER: Warren H 

PROVIDER: S-EPMC11249832 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature