Comparative efficacies of the three echinocandins for Candida auris candidemia: real world evidence from a tertiary centre in India.

ABSTRACT: Though echinocandins are the first line of therapy for C. auris candidemia, there is little clinical data to guide the choice of therapy within this class. This was the first study to compare the three echinocandins in terms of efficacy and outcomes for C. auris candidemia. This was a retrospective analysis of 82 episodes of candidemia caused by C. auris comparing outcomes across the three echinocandins. Majority patients in our study were treated with micafungin. Susceptibility rates were the lowest for caspofungin (35.36% resistance), with no resistance reported for the other two echinocandins. When a susceptible echinocandin was chosen, caspofungin resistance was not a factor significantly associated with mortality. Also, when a susceptible echinocandin was used for therapy, the choice

SUBMITTER: Prayag PS 

PROVIDER: S-EPMC11250272 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature