The hemodynamic and geometric characteristics of carotid artery atherosclerotic plaque formation.

ABSTRACT:

Background

Ischemic stroke, which has a high incidence, disability, and mortality rate, is mainly caused by carotid atherosclerotic plaque. The difference in the geometric structures of the carotid arteries inevitably leads to the variability in the local hemodynamics, which plays a key role in the formation of carotid atherosclerosis. At present, the combined mechanisms of hemodynamic and geometric in the formation of carotid atherosclerotic plaque are not clear. Thus, this study characterized the geometric and hemodynamic characteristics of carotid atherosclerotic plaque formation using four-dimensional (4D) flow magnetic resonance imaging (MRI).

Methods

Ultimately, 122 carotid arteries from 61 patients were examined in this study. According to the presence of plaques at t

SUBMITTER: Han N 

PROVIDER: S-EPMC11250319 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature