Point-shear wave elastography generated by acoustic radiation force impulse in chronic pancreatitis.

ABSTRACT:

Background

Transcutaneous point-shear wave elastography (p-SWE) performed using an acoustic radiation force impulse can be used to quantify pancreatic stiffness in chronic pancreatitis (CP). We aimed to evaluate its usefulness to diagnose and monitor CP.

Methods

175 participants were included in this prospective study including patients with CP (n = 65), liver cirrhosis (LC; n = 60), alcohol abuse (n = 10) and healthy controls (n = 40). Point-shear wave elastography of the pancreas was performed and quantified as median shear wave velocity (SWV). In the same way, p-SWE of the spleen served as a marker of portal hypertension. The M-ANNHEIM Severity score was used as global marker for disease activity in CP.

Results

Compared to healthy controls, pancreatic SWV was signi

SUBMITTER: Wekerle M 

PROVIDER: S-EPMC11250422 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature