Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish.

ABSTRACT: Jellyfish exhibit innovative swimming patterns that contribute to exploring the origins of animal locomotion. However, the genetic and cellular basis of these patterns remains unclear. Herein, we generated chromosome-level genome assemblies of two jellyfish species, Turritopsis rubra and Aurelia coerulea, which exhibit straight and free-swimming patterns, respectively. We observe positive selection of numerous genes involved in statolith formation, hair cell ciliogenesis, ciliary motility, and motor neuron function. The lineage-specific absence of otolith morphogenesis- and ciliary movement-related genes in T. rubra may be associated with homeostatic structural statocyst loss and straight swimming pattern. Notably, single-cell transcriptomic analyses covering key developmental stages revea

SUBMITTER: Dong Z 

PROVIDER: S-EPMC11250803 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature