Effect of long-term use of antipsychotics on the ventricular repolarization index.

ABSTRACT:

Background

The risk of arrhythmia is usually assessed by the length of the corrected QT interval (QTc) when patients use antipsychotics. Prolonged QTc intervals are thought to increase the probability of malignant ventricular arrhythmias, and if we focus only on the QTc interval, we may be influenced by a single factor and make decisions that are not conducive to effective treatment. The index of cardiac electrophysiological balance (iCEB) is considered more valuable than the QTc for predicting drug-induced arrhythmias. It has been used in clinical practice, but no studies have observed changes in this index after the use of antipsychotics.

Objective

To investigate the changes in ventricular repolarization indices and the occurrence of arrhythmias in patients who have been u

SUBMITTER: Liu Q 

PROVIDER: S-EPMC11250928 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature