The seizure severity score: a quantitative tool for comparing seizures and their response to therapy.

ABSTRACT: Objective.Epilepsy is a neurological disorder characterized by recurrent seizures which vary widely in severity, from clinically silent to prolonged convulsions. Measuring severity is crucial for guiding therapy, particularly when complete control is not possible. Seizure diaries, the current standard for guiding therapy, are insensitive to the duration of events or the propagation of seizure activity across the brain. We present a quantitative seizure severity score that incorporates electroencephalography (EEG) and clinical data and demonstrate how it can guide epilepsy therapies.Approach.We collected intracranial EEG and clinical semiology data from 54 epilepsy patients who had 256 seizures during invasive, in-hospital presurgical evaluation. We applied an absolute slope a

SUBMITTER: Pattnaik AR 

PROVIDER: S-EPMC11250994 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature