Prenatal oxidative stress and rapid infant weight gain.

ABSTRACT:

Background and objectives

Infant weight patterns predict subsequent weight outcomes. Rapid infant weight gain, defined as a >0.67 increase in weight-for-age z-score (WAZ) between two time points in infancy, increases obesity risk. Higher oxidative stress, an imbalance between antioxidants and reactive oxygen species, has been associated with low birthweight and paradoxically also with later obesity. We hypothesized that prenatal oxidative stress may also be associated with rapid infant weight gain, an early weight pattern associated with future obesity.

Methods

Within the NYU Children's Health and Environment Study prospective pregnancy cohort, we analyzed associations between prenatal lipid, protein, and DNA urinary oxidative stress biomarkers and infant weight data. Primar

SUBMITTER: Duh-Leong C 

PROVIDER: S-EPMC11251034 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature