CircRNA and lncRNA-associated competing endogenous RNA networks in medulloblastoma: a scoping review.

ABSTRACT:

Background

Medulloblastoma is one of the common primary central nervous system (CNS) malignancies in pediatric patients. The main treatment is surgical resection preceded and/or followed by chemoradiotherapy. However, their serious side effects necessitate a better understanding of medulloblastoma biology to develop novel therapeutic options.

Main body

Circular RNA (circRNA) and long non-coding RNA (lncRNA) regulate gene expression via microRNA (miRNA) pathways. Although growing evidence has highlighted the significance of circRNA and lncRNA-associated competing endogenous RNA (ceRNA) networks in cancers, no study has comprehensively investigated them in medulloblastoma. For this aim, the Web of Science, PubMed, Scopus, and Embase were systematically searched to obtain the r

SUBMITTER: Nejadi Orang F 

PROVIDER: S-EPMC11251335 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature