Isolation and characterisation of Leishmania (Leishmania) infantum from cutaneous leishmaniasis patients in northeast Brazil.

ABSTRACT:

Background

In Brazil, Leishmania (Leishmania) infantum is a widely distributed protozoan parasite. The human leishmaniasis caused by this species is often associated with visceral form. Tegumentary leishmaniasis (TL) cases due to L. (L.) infantum in the country are considered rare but may be underestimated. Although probably uncommon, these cases represent a new challenge to the prevention and control of leishmaniasis.

Objectives

Here, we describe two distinct cases of TL with atypical clinical presentations caused by L. (L.) infantum.

Methods and findings

Parasites were isolated from cutaneous lesions of the two patients and typed as L. (L.) infantum after sequencing of the ribosomal DNA internal transcribed spacer. The dermotropic L. (L.) infantum isolates were comp

SUBMITTER: Soares GHC 

PROVIDER: S-EPMC11251414 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature