The existence of adrenal insufficiency in patients with COVID-19 pneumonia.

ABSTRACT:

Introduction

Infection with SARS-CoV-2 virus may result in long COVID, a syndrome characterized by symptoms such as dyspnea, cardiac abnormalities, cognitive impairment, and fatigue. One potential explanation for these symptoms is hypocortisolism.

Objective

To evaluate the prevalence of hypocortisolism in patients with a history of COVID-19 pneumonia.

Methods

Cross-sectional study of patients who were aged ≥18 years and had a 3-month history of radiography-confirmed COVID-19 pneumonia. Exclusion criteria included current or previous treatment with glucocorticoids and use of an oral contraceptive. Adrenal function was evaluated using a low dose (1ug) corticotropin stimulation test (CST). Serum cortisol levels were measured at 0, 30, and 60 minutes, and baseline plasma

SUBMITTER: Porntharukchareon T 

PROVIDER: S-EPMC11251879 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature