Prenatal and childhood air pollution exposure, cellular immune biomarkers, and brain connectivity in early adolescents.

ABSTRACT:

Introduction

Ambient air pollution is a neurotoxicant with hypothesized immune-related mechanisms. Adolescent brain structural and functional connectivity may be especially vulnerable to ambient pollution due to the refinement of large-scale brain networks during this period, which vary by sex and have important implications for cognitive, behavioral, and emotional functioning. In the current study we explored associations between air pollutants, immune markers, and structural and functional connectivity in early adolescence by leveraging cross-sectional sex-stratified data from the Adolescent Brain Cognitive Development℠ Study®.

Methods

Pollutant concentrations of fine particulate matter, nitrogen dioxide, and ozone were assigned to each child's primary residential address

SUBMITTER: Cotter DL 

PROVIDER: S-EPMC11252082 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature