Reproducibility analysis of bioimpedance-based self-developed live cell assays.

ABSTRACT: Bioimpedance spectrum (BIS) measurements have a great future in in vitro experiments, meeting all the requirements for non-destructive and label-free methods. Nevertheless, a real basic research can provide the necessary milestones to achieve the success of the method. In this paper a self-developed technology-based approach for in vitro assays is proposed. Authors invented a special graphene-based measuring plate in order to assess the high sensitivity and reproducibility of introduced technique. The design of the self-produced BIS plates maximizes the detection capacity of qualitative changes in cell culture and it is robust against physical effects and artifacts. The plates do not influence the viability and proliferation, however the results are robust, stable and reproducible regardle

SUBMITTER: Vizvari Z 

PROVIDER: S-EPMC11252348 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature