Betacyanins from red pitahaya (Hylocereus polyrhizus) exhibit antiviral response against influenza A virus.

ABSTRACT: Seasonal influenza affects millions of lives worldwide, with the influenza A virus (IAV) responsible for pandemics and annual epidemics, causing the most severe illnesses resulting in patient hospitalizations or death. With IAV threatening the next global influenza pandemic, it is a race against time to search for antiviral drugs. Betacyanins are unique nitrogen-containing and water-soluble reddish-violet pigments that have been reported to possess antiviral properties against the dengue virus. This study aimed to examine the antiviral effect of betacyanins from red pitahaya (Hylocereus polyrhizus) on IAV-infected lung epithelial A549 cells. HPLC and LC-MS analysis of extracted betacyanin showed four betacyanins in the betacyanin fraction: phyllocactin, hylocerenin, betanin, and iso

SUBMITTER: Lim CM 

PROVIDER: S-EPMC11252771 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature