Risk factors and development of machine learning diagnostic models for lateral lymph node metastasis in rectal cancer: multicentre study.

ABSTRACT:

Background

The diagnostic criteria for lateral lymph node metastasis in rectal cancer have not been established. This research aimed to investigate the risk factors for lateral lymph node metastasis and develop machine learning models combining these risk factors to improve the diagnostic performance of standard imaging.

Method

This multicentre prospective study included patients who underwent lateral lymph node dissection without preoperative treatment for rectal cancer between 2017 and 2019 in 15 Japanese institutions. First, preoperative clinicopathological factors and magnetic resonance imaging findings were evaluated using multivariable analyses for their correlation with lateral lymph node metastasis. Next, machine learning diagnostic models for lateral lymph node meta

SUBMITTER: Kasai S 

PROVIDER: S-EPMC11252850 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature