Distal but not local auditory information supports spatial representations by place cells.

ABSTRACT: Sound is an important navigational cue for mammals. During spatial navigation, hippocampal place cells encode spatial representations of the environment based on visual information, but to what extent audiospatial information can enable reliable place cell mapping is largely unknown. We assessed this by recording from CA1 place cells in the dark, under circumstances where reliable visual, tactile, or olfactory information was unavailable. Male rats were exposed to auditory cues of different frequencies that were delivered from local or distal spatial locations. We observed that distal, but not local cue presentation, enables and supports stable place fields, regardless of the sound frequency used. Our data suggest that a context dependency exists regarding the relevance of auditory informa

SUBMITTER: Dolon Vera L 

PROVIDER: S-EPMC11252853 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature