Exposure to Air Pollution, Genetic Susceptibility, and Psoriasis Risk in the UK.

ABSTRACT:

Importance

Psoriasis is a common autoinflammatory disease influenced by complex interactions between environmental and genetic factors. The influence of long-term air pollution exposure on psoriasis remains underexplored.

Objective

To examine the association between long-term exposure to air pollution and psoriasis and the interaction between air pollution and genetic susceptibility for incident psoriasis.

Design, setting, and participants

This prospective cohort study used data from the UK Biobank. The analysis sample included individuals who were psoriasis free at baseline and had available data on air pollution exposure. Genetic analyses were restricted to White participants. Data were analyzed between November 1 and December 10, 2023.

Exposures

Exposure to

SUBMITTER: Wu J 

PROVIDER: S-EPMC11252902 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature