S-EPMC11253179 - A water-soluble, cell-permeable Mn(ii) sensor enables visualization of manganese dynamics in live mammalian cells† † Electronic supplementary information (ESI) available: Details of DFT and TDDFT calculations, synthesis, and characterization of novel molecules via LC-ESI-MS, 1H-NMR and 13C-NMR, fluorescence experiments, cytotoxicity assay, cell studies, photostability assay, Mn2+ uptake studies, TCSPC and FLIM experiments (PDF). Supporting videos of live imaging of Mn2+ dynamics: Videos S1 and S2 (MP4). See DOI: https://doi.org/10.1039/d4sc00907j