The neurophysiological brain-fingerprint of Parkinson's disease.

ABSTRACT:

Background

Research in healthy young adults shows that characteristic patterns of brain activity define individual "brain-fingerprints" that are unique to each person. However, variability in these brain-fingerprints increases in individuals with neurological conditions, challenging the clinical relevance and potential impact of the approach. Our study shows that brain-fingerprints derived from neurophysiological brain activity are associated with pathophysiological and clinical traits of individual patients with Parkinson's disease (PD).

Methods

We created brain-fingerprints from task-free brain activity recorded through magnetoencephalography in 79 PD patients and compared them with those from two independent samples of age-matched healthy controls (N = 424 total). We deco

SUBMITTER: da Silva Castanheira J 

PROVIDER: S-EPMC11253223 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature