Assessing the therapeutic potential of long-chain isomaltooligosaccharides in diabetic and hyperlipidemic rats.

ABSTRACT:

Background

The global rise in diabetes prevalence necessitates effective treatments. Rats, mimicking physiological changes seen in Type 2 diabetes, serve as valuable models for studying metabolic disorders. Natural health supplements, especially prebiotics, are gaining interest for improving metabolic health. Isomaltooligosaccharides (IMOs), classified as functional oligosaccharides and prebiotics, have attracted attention due to their beneficial effects on gut microbiota balance and cholesterol reduction. However, commercial IMOs often contain undesirable sugars, leading to the development of long-chain IMOs with enhanced prebiotic properties.

Methods

This study assessed the therapeutic potential of long-chain IMOs derived from Bacillus subtilis strain AP-1 compared to inul

SUBMITTER: Reamtong O 

PROVIDER: S-EPMC11253390 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature