Identification of key modules and hub genes involved in regulating the feather follicle development of Wannan chickens using WGCNA.

ABSTRACT: Carcass appearance is important economic trait, which affects customers in making purchase decisions. Both density and diameter of feather follicles are two important indicators of carcass appearance. However, the regulatory network and key genes be involved in feather follicle development remain poorly understood. To identify key genes and modules that involved in feather follicle development in chickens, 16 transcriptome datasets of Wannan chickens skin tissue (3 birds at the E9, E11, and E14, respectively, and 7 birds at the 12W) were used for weighted gene co-expression network analysis (WGCNA) analysis, and 12 skin tissue samples (3 birds for each stage) were selected for DEGs analysis. A total of 5,025, 2,337, and 10,623 DEGs were identified in 3 comparison groups, including the E9 v

SUBMITTER: Wang J 

PROVIDER: S-EPMC11253687 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature