Serological diagnosis of strongyloidiasis: An evaluation of three commercial assays.

ABSTRACT:

Background

Strongyloidiasis is caused by a neglected nematode, manifesting as chronic intestinal infection with potentially severe manifestations. The disease is an emerging problem in non-endemic countries affecting travelers and migrants. Diagnosis of strongyloidiasis is hampered by the lack of standardization and absence of a gold standard. Since adequate direct methods to detect the motile larvae in stool samples are not widely available, other techniques such as serology have been developed.

Methods

We evaluated three commercial ELISA kits (DRG Instruments, IVD Research, and Bordier Affinity Products) to detect IgG antibodies against Strongyloides stercoralis assays utilizing serum samples from travelers with microscopically confirmed strongyloidiasis (n = 50) and other

SUBMITTER: Weitzel T 

PROVIDER: S-EPMC11253981 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature